sign in
>ptx_
Program Therapeutics

FOUNDERS

RNA structure engineers

Paloma Giangrande
Translation + Delivery
SVP Discovery at Orbital
Raghav Poudyal
RNA Chemistry PCM
Head of PCM at Orbital
Ben Holmes
AI + Sequence Design
Head of Data at Orbital

TECHNOLOGY

RNA Pillar
RNA PAYLOAD
  • Scalable
  • Potent
  • Immunoquiescent
Delivery Pillar
DELIVERY
  • Safe
  • Biodegradable
  • Targeted
AI Pillar
AI DESIGN
  • Durable
  • Programmable
  • Re-dosable

URICASE DELIVERY

LNP delivers ancestral uricase mRNA
→
LIVER
Hepatocyte uptake
→
Functional uricase protein expressed